a. RhoGAM® incompatibility occurs when the Rh-negative pregnant patient carries an Rh-positive fetus. The patient’s body reacts to the “foreign” fetus blood type. The mother produces antibodies that in-turn causes destruction of the fetus red blood cells (hemolysis). Hemolysis of the fetus red blood cells deprives the fetus of oxygen (erythroblastosis fetalis).
b. The treatment for Rh incompatability is given below.
(1) RhoGAM® (immune globulin) administered 72 hours following the birth of an Rh-positive child will eliminate maternal isoimmunization. Refer to figure 1-2.
(2) An Rh-negative patient whose sex partner is Rh-positive, who aborts or has an ectopic pregnancy, should receive RhoGAM®. This is essential to prevent the patient from developing Rh-positive antibodies.
c. Nursing implications are listed below.
(1) Follow the obstetrics (OB) practitioner’s or physician’s orders for drawing of Rh antibody titer.
(2) Follow delivery room standing operating procedure (SOP) to obtain cord blood sample to determine baby’s blood type
Pregnancy category of the specific generic scientific name or ingredients. Category may be:
A: Controlled studies in pregnant women demonstrate no fetal risk.
B: Controlled animal studies have not shown a fetal risk but there are no studies done on women OR controlled studies in animals have shown a fetal risk that was not reproduced in controlled human studies.
C: Controlled animal studies have demonstrated adverse fetal effects and there are no human studies or there are no controlled studies in humans or animals
D: Controlled studies in humans demonstrate adverse fetal effects but the benefits of using the drug are greater than the risks (eg, propylthiouracil)
X: Controlled studies in animals and humans have demonstrated adverse fetal effects or there is evidence of fetal risk based on human experience. The risk of using these drugs outweighs any possible benefit. The drug is absolutely contraindicated in pregnancy (eg, misoprostol, warfarin, isotretinoin).
Most drugs prescribed for pregnant women are Category A, B or C.
Not sure if these are all correct… I am going to put it on my to do list (look up info for all meds listed)
Antidotes to Common Medications
Clinical Pathway/ Cardiotoxic OD see SOURCE for more detail
..More PHARM Review NCLEX cram