Human Development Timeline
Outer layer is serosa (squamous epithelium + connective tissue);
inner circular and outer muscular layers (smooth);
lamina propria connective tissue from mucosa to muscularis.
Infundibulum—fimbriated (fringe) end that scans the ovary and captures the secondary oocyte
Ampulla—expanded region (like a trumpet) where the oocyte is fertilized.
Isthmus—narrow region that connects to the uterus at the interstitial (intramural) region
The wall varies in the inside diameter. Note that the muscular layer (orange) is much greater in proportion to the inside diameter in the isthmus. This part is more of a transport tube. The ampulla is expanded to allow movement, transport and fertilization. The Infundibulum is very tortuous with many folds in the mucosa.
Structured to nourish and move the oocyte and fertilized embryo to the uterus.
Ciliated cells: Movement is done by ciliated cells (cilia is very sensitive to estrogens; if estrogen level drops, cells will lose cilia). Cilia beat toward uterus which means the spermatozoa must swim upstream, against a current of liquid secreted by Peg Cells.
Peg cells have no cilia. They secrete a nutritive fluid that facilitates capacitation of spermatozoa. Note: is this required? What about in vitro fertilization?
Also, secretion from Peg cells nourishes embryo as it passes down the 12 cm tube.
Peg cells also secrete fluid that inhibits microorganisms that could invade from the peritoneal cavity.
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Development of child with cerebral palsy